Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22701403 | 0.94 | MAPT (0.56) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL20268581 | 0.82 | MAPT (0.59) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL10813238 | 0.82 | GAA (0.61) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL14247246 | 0.79 | MAPT (0.58) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL20268378 | 0.78 | MAPT (0.56) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL11789717 | 0.78 | CYP3A4 (0.43) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL24208169 | 0.78 | ALDH1A1 (0.45) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL24208167 | 0.78 | MAPT (0.64) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL5080900 | 0.77 | MAPT (0.64) | GAAMAPTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL2602405 | 0.77 | MAPT (1.00) | GAAMAPTTDP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951920-A | Permselective polymeric membrane prepared from polybenzimidazoles | TEIJIN LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |