Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792172 | 0.94 | GAA (0.62) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL20268581 | 0.90 | MAPT (0.59) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL10813238 | 0.85 | GAA (0.61) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL22683200 | 0.83 | MAPT (0.61) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11647101 | 0.83 | MAPT (0.55) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL22102775 | 0.82 | MAPT (0.65) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9013602 | 0.81 | ACHE (0.68) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL15831 | 0.81 | ACHE (0.68) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL20285584 | 0.81 | MAPT (0.51) | MAPTGAATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL7974346 | 0.77 | RAPGEF4 (0.55) | MAPTGAATDP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |