Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397801 | 0.82 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6960232 | 0.77 | SMN1; SMN2 (0.42) | BCL2MCL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7371787 | 0.75 | MAPK1 (0.37) | BCL2MCL1MEN1KMT2AMAPT | |
| SCHEMBL11792467 | 0.75 | MEN1 (0.45) | BCL2MCL1MEN1KMT2AMAPT | |
| SCHEMBL6958076 | 0.74 | SMN1; SMN2 (0.58) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8536182 | 0.73 | ALDH1A1 (0.36) | BCL2MCL1MEN1KMT2AMAPT | |
| SCHEMBL6965057 | 0.72 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6965119 | 0.72 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6959912 | 0.72 | ATM (0.43) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9050073 | 0.71 | ADORA3 (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |