Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.64 |
| ▸ | ACE | P12821 | 6/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265066 | 1.00 | FAAH (0.64) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL987963 | 1.00 | FAAH (0.64) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL15692406 | 0.94 | PSMB5 (0.66) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL7893850 | 0.92 | MME (0.63) | FAAHACEITGB3ITGA2BMME | |
| SCHEMBL9716668 | 0.91 | FAAH (0.73) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL2565532 | 0.91 | FAAH (0.73) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL15155391 | 0.91 | FAAH (0.73) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL8467930 | 0.89 | FAAH (0.79) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL9666252 | 0.89 | FAAH (0.79) | FAAHACEPSMB5ITGB3ITGA2B | |
| SCHEMBL16449189 | 0.89 | PSMB5 (0.60) | FAAHACEPSMB5CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983162-A | Optical resolution of alkyl esters of DL-phenylalanine | G. D. SEARLE & CO. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3941831-A | Resolution of alkyl esters of DL-phenylalanine | G. D. SEARLE & CO. (US) | 1976-03-02 | — | — | US | disclosed |