SCHEMBL2565532

SCHEMBL2565532

CCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.73
PSMB5 P28074 3/20 0.62
ACE P12821 4/20 0.59
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58
CTSB P07858 1/20 0.56
CTSG P08311 1/20 0.56
CMA1 P23946 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716668 1.00 FAAH (0.73) FAAHPSMB5ACEITGB3ITGA2B
SCHEMBL15155391 1.00 FAAH (0.73) FAAHPSMB5ACEITGB3ITGA2B
SCHEMBL8467930 0.95 FAAH (0.79) FAAHPSMB5ACEITGB3ITGA2B
SCHEMBL9666252 0.95 FAAH (0.79) FAAHPSMB5ACEITGB3ITGA2B
SCHEMBL1815011 0.94 FAAH (0.81) FAAHPSMB5ITGB3ITGA2B
SCHEMBL22494096 0.94 FAAH (0.81) FAAHPSMB5ITGB3ITGA2B
SCHEMBL9716617 0.94 FAAH (0.81) FAAHPSMB5ITGB3ITGA2B
SCHEMBL22494095 0.94 FAAH (0.81) FAAHPSMB5ITGB3ITGA2B
SCHEMBL22494097 0.94 FAAH (0.81) FAAHPSMB5ITGB3ITGA2B
SCHEMBL9506671 0.94 FAAH (0.81) FAAHPSMB5ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140127144-A1 Flavour Modifying Compounds GIVAUDAN S. A. (CH) 2014-05-08 US claimed
WO-2013114173-A1 A NOVEL PROCESS FOR THE PREPARATION OF SITAGLIPTIN SMILAX LABORATORIES LIMITED (IN) 2013-08-08 WO claimed
CN-119486739-A α4β1/7Integrin ligand conjugated compounds and uses thereof 阿达尔克斯制药有限公司 2025-02-18 CN disclosed
CN-118255830-A S1PR2 modulators and uses thereof 北京昌平实验室 2024-06-28 CN disclosed
EP-4386090-A1 METHOD FOR DETERMINING AND IMPROVING THE POTENTIAL EFFICACY OF ANTICANCER TREATMENT ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (FR) 2024-06-19 EP disclosed
CN-116926140-A A fatty acylated amino acid with effect of enhancing or improving food taste, and its preparation method 华南理工大学 2023-10-24 CN disclosed
US-11527306-B2 Streamlined method for analytical validation of biochemicals detected using an untargeted mass-spectrometry platform METABOLON, INC. (US) 2022-12-13 US disclosed
CN-115340468-A (R) -deuterated phenylalanine derivative and preparation method thereof 西南大学 2022-11-15 CN disclosed
US-20210233616-A1 A Streamlined Method for Analytical Validation of Biochemicals Detected Using an Untargeted Mass-Spectrometry Platform METABOLON, INC. 2021-07-29 US disclosed
EP-3694646-A1 A STREAMLINED METHOD FOR ANALYTICAL VALIDATION OF BIOCHEMICALS DETECTED USING AN UNTARGETED MASS-SPECTROMETRY PLATFORM Metabolon, Inc. (US) 2020-08-19 EP disclosed
WO-2019074757-A1 A STREAMLINED METHOD FOR ANALYTICAL VALIDATION OF BIOCHEMICALS DETECTED USING AN UNTARGETED MASS-SPECTROMETRY PLATFORM METABOLON, INC. (US) 2019-04-18 WO disclosed
EP-1660112-A2 ORALLY ADMINISTERED SMALL PEPTIDES SYNERGIZE STATIN ACTIVITY The Regents of the University of California (US) 2006-05-31 EP disclosed
WO-2006034056-A2 G-TYPE PEPTIDES AND OTHER AGENTS TO AMELIORATE ATHEROSCLEROSIS AND OTHER PATHOLOGIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-03-30 WO disclosed
EP-1562624-A2 ORALLY ADMINISTERED PEPTIDES SYNERGIZE STATIN ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-08-17 EP disclosed
WO-2005016280-A2 ORALLY ADMINISTERED SMALL PEPTIDES SYNERGIZE STATIN ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-24 WO disclosed
WO-2004034977-A2 ORALLY ADMINISTERED PEPTIDES SYNERGIZE STATIN ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-04-29 WO disclosed
EP-0178911-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1992-01-22 EP disclosed
CN-1043133-A imidazole-containing peptide and preparation method thereof TANABE SEIYAKU CO (JP) 1990-06-20 CN disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140127144-A1 Flavour Modifying Compounds TAS2R1, TAS1R2, TAS2R5 FAAH 1516/4885PSMB5 973/4885ACE 2482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.