Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794466 | 1.00 | PGR (0.61) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL7854625 | 0.84 | PGR (0.58) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL7859913 | 0.83 | PGR (0.56) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL6012018 | 0.80 | AR (0.52) | PGRNR3C1SHBGARMEN1 | |
| SCHEMBL11424896 | 0.78 | PGR (0.70) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL8425124 | 0.78 | PGR (0.62) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL6842375 | 0.77 | PGR (0.75) | PGRNR3C1CYP3A4ABCB11LMNA | |
| SCHEMBL6140132 | 0.76 | PGR (0.50) | PGRNR3C1CYP3A4ABCB11LMNA | |
| Norgestomet SCHEMBL140382 | 0.76 | PGR (1.00) | PGRNR3C1CYP3A4ABCB11LMNA | |
| Norgestomet SCHEMBL11794624 | 0.76 | PGR (1.00) | PGRNR3C1CYP3A4ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941880-A | Method for use of 11-lower alkyl steroids | G. D. SEARLE & CO. (US) | 1976-03-02 | — | — | US | claimed |
| US-3941880-A | Method for use of 11-lower alkyl steroids | G. D. SEARLE & CO. (US) | 1976-03-02 | — | — | US | disclosed |