Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.52 |
| ▸ | PGR | P06401 | 8/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.41 |
| ▸ | SHBG | P04278 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793678 | 0.80 | PGR (0.61) | ARPGRSHBGMEN1KMT2A | |
| SCHEMBL6011910 | 0.77 | AR (0.43) | ARPGRSHBG | |
| SCHEMBL9340441 | 0.73 | AR (0.59) | ARPGRNR3C2SHBGNR3C1 | |
| SCHEMBL24102415 | 0.73 | AR (0.82) | ARPGRNR3C2MEN1KMT2A | |
| SCHEMBL7859913 | 0.71 | PGR (0.56) | ARPGRSHBGMEN1KMT2A | |
| SCHEMBL6017673 | 0.71 | SHBG (0.52) | ARPGRNR3C2SHBGNR3C1 | |
| SCHEMBL25863642 | 0.71 | AR (0.93) | ARPGRNR3C2SHBGMEN1 | |
| SCHEMBL25863523 | 0.71 | AR (0.93) | ARPGRNR3C2SHBGMEN1 | |
| SCHEMBL25863521 | 0.71 | AR (0.93) | ARPGRNR3C2SHBGMEN1 | |
| SCHEMBL24102572 | 0.70 | AR (0.79) | ARPGRNR3C2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272196-B1 | METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA,11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE | US GOV HEALTH & HUMAN SERV (US) | 2006-08-02 | — | — | EP | claimed |
| EP-1379253-B1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA,11BETA-DIMETHYL-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | US GOV HEALTH & HUMAN SERV (US) | 2006-03-29 | — | — | EP | disclosed |