Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | SHBG | P04278 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norethandrolone SCHEMBL147638 | 0.81 | LMNA (0.71) | PGRNR3C1LMNACYP3A4SLC6A4 | |
| Norethandrolone SCHEMBL23801611 | 0.81 | LMNA (0.71) | PGRNR3C1LMNACYP3A4SLC6A4 | |
| SCHEMBL4587006 | 0.77 | MAPT (0.55) | PGRNR3C1LMNACYP3A4ABCB11 | |
| SCHEMBL11793678 | 0.76 | PGR (0.61) | PGRNR3C1LMNACYP3A4SLC6A4 | |
| SCHEMBL11794466 | 0.76 | PGR (0.61) | PGRNR3C1LMNACYP3A4SLC6A4 | |
| SCHEMBL9811566 | 0.75 | PGR (0.52) | PGRNR3C1LMNACYP3A4SLC6A4 | |
| SCHEMBL5501842 | 0.75 | SERPINA6 (0.64) | PGRNR3C1LMNACYP3A4ESR1 | |
| SCHEMBL908750 | 0.74 | CYP19A1 (0.64) | PGRLMNASHBGTSHRALDH1A1 | |
| SCHEMBL12902157 | 0.74 | CYP19A1 (0.64) | PGRLMNASHBGTSHRALDH1A1 | |
| Norethandrolone SCHEMBL13724392 | 0.74 | SHBG (0.75) | PGRNR3C1LMNACYP3A4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | NR5A1, HSD17B11, HSD11B1 | PGR 174/4885NR3C1 31/4885LMNA 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.