Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792711 | 0.92 | LMNA (0.54) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL13019177 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL21835519 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL1433826 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL15689845 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL13243124 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL19059876 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL1847445 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL1847443 | 0.91 | LMNA (0.61) | LMNAALDH1A1TP53DNMT1GMNN | |
| SCHEMBL12415519 | 0.90 | LMNA (0.69) | LMNAALDH1A1TP53DNMT1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998807-A | ARABINOFURANOSYL CYTOSINES AND METHODS OF MAKING | SYNTEX (U.S.A.) INC. (US) | 1976-12-21 | — | — | US | disclosed |