Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433826 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL13019177 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL19059876 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL21835519 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL1847443 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL15689845 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL13243124 | 1.00 | LMNA (0.61) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL14146164 | 0.91 | ALDH1A1 (0.52) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL11794055 | 0.91 | LMNA (0.58) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL15702571 | 0.91 | ALDH1A1 (0.63) | LMNAALDH1A1TP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130008238-A1 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE | BIGATTI ETTORE (IT) | 2013-01-10 | — | — | US | disclosed |
| EP-2324042-B1 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE | SICOR INC (US) | 2012-11-28 | — | — | EP | disclosed |
| EP-2520581-A1 | Method for the determination the purity of 5-Azacytidine | Sicor, Inc. (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-2324042-A1 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE | Sicor, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010017374-A1 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE | SICOR INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20100035354-A1 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE | SICOR INC. | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035354-A1 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE | TET2, AZI2, DNMT1 | LMNA 1206/4885ALDH1A1 481/4885TP53 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.