Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MTOR | P42345 | 2/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | THPO | P40225 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | HBB | P68871 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | HINT1 | P49773 | 3/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | ATIC | P31939 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689915 | 1.00 | LMNA (0.69) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL11794055 | 0.90 | LMNA (0.58) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL6369753 | 0.89 | DNMT1 (0.66) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL19888757 | 0.86 | DNMT1 (0.72) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL15689845 | 0.85 | LMNA (0.61) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL19059876 | 0.85 | LMNA (0.61) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL13243124 | 0.85 | LMNA (0.61) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL1847445 | 0.85 | LMNA (0.61) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL21835519 | 0.85 | LMNA (0.61) | LMNADNMT1ALDH1A1TP53MTOR | |
| SCHEMBL13019177 | 0.85 | LMNA (0.61) | LMNADNMT1ALDH1A1TP53MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201800-A1 | AZACITIDINE PROCESS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201800-A1 | AZACITIDINE PROCESS AND POLYMORPHS | AZI2, DNMT3A, DCTD | LMNA 1979/4885DNMT1 4/4885ALDH1A1 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.