Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789033 | 0.84 | MAPK1 (0.57) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11796428 | 0.81 | SMN1; SMN2 (0.58) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11795245 | 0.80 | P2RX1 (0.53) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27754113 | 0.80 | KMT2A (0.61) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18283381 | 0.78 | MAPT (0.57) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6659637 | 0.74 | L3MBTL1 (0.57) | RORCMAPTNPC1ALDH1A1LMNA | |
| SCHEMBL4175674 | 0.73 | KMT2A (0.40) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2963423 | 0.73 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL8042285 | 0.71 | MAPT (0.62) | RORCMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7156146 | 0.70 | CRHBP (0.73) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974204-A | PARASITICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3966964-A | LIVER FLUKES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |