Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159721 | 0.84 | CRHBP (0.67) | L3MBTL1CYP1A2HPGDCYP2C19KCNMA1 | |
| SCHEMBL19583271 | 0.81 | KMT2A (0.59) | KCNMA1LMNARORCCRHBPCRHR2 | |
| SCHEMBL25434232 | 0.79 | TNF (0.57) | L3MBTL1CYP1A2HPGDCYP2C19KCNMA1 | |
| SCHEMBL9867130 | 0.78 | CXCR2 (0.58) | L3MBTL1CYP1A2HPGDCYP2C19KCNMA1 | |
| SCHEMBL8054226 | 0.75 | CRHBP (0.58) | L3MBTL1KCNMA1LMNAMAPTCRHBP | |
| SCHEMBL27754113 | 0.75 | KMT2A (0.61) | CYP1A2HPGDCYP2C19POLBLMNA | |
| SCHEMBL11794196 | 0.74 | RORC (0.47) | CYP1A2CYP2C19POLBLMNAMAPT | |
| SCHEMBL7161319 | 0.73 | CRHBP (0.77) | L3MBTL1KCNMA1POLBLMNAMAPT | |
| SCHEMBL34474784 | 0.73 | RORC (0.73) | CYP1A2CYP2C19KCNMA1POLBLMNA | |
| SCHEMBL18146442 | 0.72 | RORC (0.81) | CYP1A2CYP2C19POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004006906-A2 | METHODS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2004-01-22 | — | — | WO | claimed |