SCHEMBL117946

SCHEMBL117946

CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ MDM2 Q00987 3/20 0.51
▸ PTPN1 P18031 2/20 0.49
▸ ITGB3 P05106 2/20 0.48
▸ ITGA2B P08514 2/20 0.48
▸ CASP3 P42574 1/20 0.48
▸ CTSL P07711 1/20 0.47
▸ CTSK P43235 1/20 0.47
▸ ABCB1 P08183 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1063199 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29349956 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29384797 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL31714182 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29358863 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL119588 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL31369598 0.97 MDM2 (0.53) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516252 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516240 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516235 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107163105-B Crystallization method of natural linaclotide 清华大学 2020-12-11 — — CN claimed
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-29 — — US disclosed
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-22 — — US disclosed
US-20230406879-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-12-21 — — US disclosed
US-20230365643-A1 PEPTIDE, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) 2023-11-16 — — US disclosed
US-11787836-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-10-17 — — US disclosed
US-11787836-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-10-17 — — US disclosed
CN-116457365-A Peptides and cosmetic and pharmaceutical compositions comprising said peptides 首尔大学医院 2023-07-18 — — CN disclosed
EP-4209500-A1 PEPTIDE, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Seoul National University Hospital (KR) 2023-07-12 — — EP disclosed
US-20230138226-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-05-04 — — US disclosed
EP-1487493-A2 CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES The Administrators of The Tulane Educational Fund (US) 2004-12-22 — — EP disclosed
EP-1435826-A2 DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF The Administrators of The Tulane Educational Fund (US) 2004-07-14 — — EP disclosed
WO-2003074551-A2 CONJUGATES OF THERAPEUTIC OR CYTOTOXIC AGENTS AND BIOLOGICALLY ACTIVE PEPTIDES THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2003-09-12 — — WO disclosed
WO-2003028527-A2 DIAGNOSTIC OR THERAPEUTIC SOMATOSTATIN OR BOMBESIN ANALOG CONJUGATES AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2003-04-10 — — WO disclosed
US-5776897-A Treating disorders by application of insulin-like growth factors and analogs CEPHALON, INC. (US) 1998-07-07 — — US disclosed
US-5703045-A NERVOUS SYSTEM DISORDERS CEPHALON, INC. (US) 1997-12-30 — — US disclosed
US-5652214-A ENHANCING SURVIVAL OF NEURONAL CELLS IN HEAD AND SPINAL CORD AFTER INJURY, ALSO TREATMENT OF AGING, ALZHEIMER*S, STROKE, EPILEPSY CEPHALON, INC. (US) 1997-07-29 — — US disclosed
EP-0604605-A4 TREATING DISORDERS BY APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS. CEPHALON INC (US) 1997-01-29 — — EP disclosed
EP-0604605-A1 TREATING DISORDERS BY APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS CEPHALON, INC. (US) 1994-07-06 — — EP disclosed
WO-1993020836-A1 TREATING DISORDERS BY APPLICATION OF INSULIN-LIKE GROWTH FACTORS AND ANALOGS CEPHALON, INC. (US) 1993-10-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885
US-20230406879-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885
US-20230138226-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885
US-11787836-B2 Method for synthesizing peptide containing N-substituted amino acid NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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