SCHEMBL1063199

SCHEMBL1063199

CC(C)(C)Oc1ccc(CC(NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ MDM2 Q00987 3/20 0.51
▸ PTPN1 P18031 2/20 0.49
▸ ITGB3 P05106 2/20 0.48
▸ ITGA2B P08514 2/20 0.48
▸ CASP3 P42574 1/20 0.48
▸ CTSL P07711 1/20 0.47
▸ CTSK P43235 1/20 0.47
▸ ABCB1 P08183 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117946 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29349956 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29384797 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL31714182 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29358863 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL119588 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL31369598 0.97 MDM2 (0.53) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516252 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516240 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516235 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751139-A Preparation method of N- (9-fluorenylmethoxycarbonyl) -O-tert-butyl-L-tyrosine 山西诺成制药有限公司 2023-09-15 — — CN claimed
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 — — EP disclosed
CN-120192365-A Colipase inhibiting peptide and application thereof 宜客美股份有限公司 2025-06-24 — — CN disclosed
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-29 — — US disclosed
US-12297293-B2 Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof NANTONG UNIVERSITY (CN) 2025-05-13 — — US disclosed
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-22 — — US disclosed
CN-119264216-B Preparation method of tyrosine serine pseudo dipeptide 成都普康唯新生物科技有限公司 2025-03-25 — — CN disclosed
CN-119684180-A Method for synthesizing thio-ester compound 南通大学 2025-03-25 — — CN disclosed
CN-119684260-A Ferritin ligand, ferritin degradation agent, pharmaceutical preparation and application 贵州大学 2025-03-25 — — CN disclosed
WO-2025043696-A1 ANTIVIRAL POLYPEPTIDE ANALOGUE 上海多米瑞生物技术有限公司 2025-03-06 — — WO disclosed
EP-1549668-A1 TUMOR TARGETING AGENTS AND USES THEREOF Karyon OY (FI) 2005-07-06 — — EP disclosed
EP-1499313-A2 HETEROCYCLIC DERIVATIVES AS OPIOID RECEPTOR MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2005-01-26 — — EP disclosed
WO-2004031221-A9 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-07-08 — — WO disclosed
WO-2004031221-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 — — WO disclosed
WO-2004031218-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 — — WO disclosed
WO-2004031219-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 — — WO disclosed
WO-2004031220-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 — — WO disclosed
US-20040010014-A1 Novel compounds as opioid receptor modulators JANSSEN PHARMACEUTICA, NV (BE) 2004-01-15 — — US disclosed
WO-2003092688-A2 HETEROCYCLIC DERIVATIVES AS OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2003-11-13 — — WO disclosed
US-6359061-B1 COMBINATORIAL LIBRARIES ARE USEFUL FOR SCREENING IN BIOLOGCAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS ISIS PHARMACEUTICALS, INC. 2002-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171494-A1 METHOD FOR SYNTHESIZING PEPTIDE CONTAINING N-SUBSTITUTED AMINO ACID NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885
US-12281141-B2 Method for synthesizing peptide containing N-substituted amino acid NPPA, VIP, DNPEP MDM4 4142/4885TP53 2781/4885MDM2 3845/4885
US-20040010014-A1 Novel compounds as opioid receptor modulators OPRL1, OPRK1, OPRM1 MDM4 4706/4885TP53 4868/4885MDM2 4043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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