SCHEMBL119588

SCHEMBL119588

CC(C)(C)Oc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ MDM2 Q00987 3/20 0.51
▸ PTPN1 P18031 2/20 0.49
▸ ITGB3 P05106 2/20 0.48
▸ ITGA2B P08514 2/20 0.48
▸ CASP3 P42574 1/20 0.48
▸ CTSL P07711 1/20 0.47
▸ CTSK P43235 1/20 0.47
▸ ABCB1 P08183 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117946 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL1063199 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29349956 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29384797 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL31714182 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL29358863 1.00 MDM4 (0.51) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL31369598 0.97 MDM2 (0.53) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516252 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516240 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3
SCHEMBL30516235 0.95 PTPN1 (0.54) MDM4TP53MDM2PTPN1ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332299-A1 COMPOUND TARGETING SSTR2, PREPARATION METHOD THEREFOR AND USE THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO LTD (CN) 2025-10-30 — — US claimed
EP-4613758-A1 COMPOUNDS TARGETING SSTR2, PREPARATION METHOD THEREFOR, AND USE THEREOF Yantai Lannacheng Biotechnology Co., Ltd. (CN) 2025-09-10 — — EP claimed
CN-119264216-B Preparation method of tyrosine serine pseudo dipeptide 成都普康唯新生物科技有限公司 2025-03-25 — — CN claimed
CN-119264216-A Preparation method of tyrosine serine pseudo dipeptide 成都普康唯新生物科技有限公司 2025-01-07 — — CN claimed
WO-2024120415-A1 COMPOUNDS TARGETING SSTR2, PREPARATION METHOD THEREFOR, AND USE THEREOF 烟台蓝纳成生物技术有限公司 2024-06-13 — — WO claimed
CN-116751139-A Preparation method of N- (9-fluorenylmethoxycarbonyl) -O-tert-butyl-L-tyrosine 山西诺成制药有限公司 2023-09-15 — — CN claimed
CN-116178500-A Preparation method of leuprorelin related compound 梯尔希(南京)药物研发有限公司 2023-05-30 — — CN claimed
CN-112159461-B Synthesis method of cetrorelix 开封明仁药业有限公司 2023-03-10 — — CN claimed
CN-112279890-B Amphiphilic polypeptide, preparation method and application 皖南医学院 2022-10-11 — — CN claimed
CN-113072620-B PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof 南通大学 2022-07-05 — — CN claimed
CN-111318187-B Chiral separation membrane based on covalent organic framework material, preparation and application thereof 南开大学 2022-04-12 — — CN claimed
US-11180533-B2 Process for the preparation of Cetrorelix acetate BIOPHORE INDIA PHARMACEUTICALS PRIVATE LIMITED (IN) 2021-11-23 — — US claimed
CN-113072620-A PD-1 targeting peptide with analgesic activity, and synthesis method and application thereof 南通大学 2021-07-06 — — CN claimed
CN-112279890-A Amphiphilic polypeptide, preparation method and application 皖南医学院 2021-01-29 — — CN claimed
CN-112159461-A Synthesis method of cetrorelix 开封明仁药业有限公司 2021-01-01 — — CN claimed
CN-111318187-A Chiral separation membrane based on covalent organic framework material, preparation and application thereof 南开大学 2020-06-23 — — CN claimed
US-5767158-A FOR BLEACHING SKIN SHISEIDO CO., LTD. (JP) 1998-06-16 — — US claimed
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 — — EP disclosed
US-4737487-A VASOACTIVE INTESTINAL PEPTIDE-ANTIULCER HYPOTENSIVE AGENT BEECHAM GROUP P.L.C. (GB) 1988-04-12 — — US disclosed
EP-0184309-A2 Peptides selected from amino-acid residues 11 to 23 of VIP BEECHAM GROUP PLC (GB) 1986-06-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332299-A1 COMPOUND TARGETING SSTR2, PREPARATION METHOD THEREFOR AND USE THEREOF SSTR2, SSTR5, SSTR3 MDM4 4630/4885TP53 2881/4885MDM2 3177/4885
US-11180533-B2 Process for the preparation of Cetrorelix acetate CYP51A1, CYP17A1, CYP11A1 MDM4 4320/4885TP53 4824/4885MDM2 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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