Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10107048 | 0.78 | KDM4E (0.32) | — | |
| SCHEMBL11792246 | 0.75 | ALDH1A1 (0.38) | PPOX | |
| SCHEMBL14073974 | 0.73 | — | — | |
| SCHEMBL11792098 | 0.70 | PPOX (0.31) | PPOX | |
| SCHEMBL21278138 | 0.68 | PIK3CD (0.41) | GAATDP1 | |
| SCHEMBL6956406 | 0.67 | — | — | |
| SCHEMBL11789091 | 0.67 | OPRL1 (0.34) | — | |
| SCHEMBL21500436 | 0.66 | PIK3CD (0.40) | GAATDP1 | |
| SCHEMBL4903842 | 0.66 | GAA (0.33) | GAATDP1 | |
| SCHEMBL11794711 | 0.64 | OPRL1 (0.40) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998954-A | 1,3(2H,4H)-Dioxoisoquinoline-4-carboxamides used as anti-inflammatory agents | PFIZER INC. (US) | 1976-12-21 | — | — | US | disclosed |