SCHEMBL10107048

SCHEMBL10107048

CC(C)N1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30
PIK3CD O00329 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11794839 0.78 GAA (0.32)
SCHEMBL21278138 0.74 PIK3CD (0.41) LMNATRIM24TRIM33PIK3CDSMN1; SMN2
SCHEMBL5849387 0.72 CSNK2A2 (0.36) LMNA
SCHEMBL21500436 0.72 PIK3CD (0.40) LMNATRIM24TRIM33PIK3CDSMN1; SMN2
SCHEMBL46223 0.70 ALDH1A1 (0.38) KDM4ELMNATRIM24TRIM33
SCHEMBL20356697 0.70 KDM4E (0.32) KDM4ELMNATRIM24TRIM33
SCHEMBL15894720 0.70 PIK3CD (0.44) KDM4ELMNAPIK3CD
SCHEMBL718764 0.69 PIK3CD (0.41) LMNAPIK3CDSMN1; SMN2
SCHEMBL4860029 0.68 KMT2A (0.34)
SCHEMBL19301942 0.67 KDM4E (0.39) KDM4ELMNAPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634390-B2 Agricultural chemicals GLOBACHEM NV (BE) 2023-04-25 US disclosed
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES REDAG CROP PROT LTD (GB) 2020-06-04 US disclosed
US-20190322627-A1 AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2019-10-24 US disclosed
US-8829078-B2 Ink composition for inkjet recording, inkjet recording method and inkjet printed article FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-20120052257-A1 INK COMPOSITION FOR INKJET RECORDING, INKJET RECORDING METHOD AND INKJET PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2012-03-01 US disclosed
US-20120041193-A1 SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES FRONTIER SCIENTIFIC, INC. (US) 2012-02-16 US disclosed
US-20120041193-A1 SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES FRONTIER SCIENTIFIC, INC. (US) 2012-02-16 US disclosed
US-20100009983-A1 5 HT RECEPTOR MEDIATED NEUROGENESIS BRAINCELLS, INC. (US) 2010-01-14 US disclosed
US-20100009983-A1 5 HT RECEPTOR MEDIATED NEUROGENESIS BRAINCELLS, INC. (US) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041193-A1 SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES BLVRB, BTD, BCL6B KDM4E 3155/4885LMNA 1514/4885TRIM24 1605/4885
US-20100009983-A1 5 HT RECEPTOR MEDIATED NEUROGENESIS HTR6, GAP43, HTR5A KDM4E 3933/4885LMNA 3909/4885TRIM24 4487/4885
US-20200172527-A1 BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES CBR3, CBR1, CYP4X1 KDM4E 1092/4885LMNA 3214/4885TRIM24 3889/4885
US-20190322627-A1 AGRICULTURAL CHEMICALS DDT, DHFR, AS3MT KDM4E 789/4885LMNA 3795/4885TRIM24 4562/4885
US-11634390-B2 Agricultural chemicals DDT, DHFR, AS3MT KDM4E 789/4885LMNA 3795/4885TRIM24 4562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.