Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630546 | 0.80 | KMT2A (0.66) | KMT2AMEN1MAOAHDAC1HDAC6 | |
| SCHEMBL2762507 | 0.77 | LMNA (0.53) | KMT2AMEN1LMNAHDAC1HDAC6 | |
| SCHEMBL11718053 | 0.75 | LMNA (0.47) | KMT2AMEN1LMNAMAOAHDAC1 | |
| SCHEMBL25138742 | 0.73 | HDAC1 (0.71) | KMT2AMEN1LMNAHDAC1HDAC6 | |
| SCHEMBL12156519 | 0.72 | LIMK2 (0.62) | KMT2AMEN1HDAC1HDAC6KDM4E | |
| SCHEMBL7119896 | 0.72 | HDAC6 (0.58) | KMT2AMEN1MAOAHDAC1HDAC6 | |
| SCHEMBL11793750 | 0.72 | LMNA (0.46) | LMNAMAOATSHRMAPK1MLYCD | |
| SCHEMBL25526179 | 0.71 | LMNA (0.48) | LMNAMAOATSHRMAPK1ALDH1A1 | |
| SCHEMBL7375547 | 0.71 | HPGD (0.64) | KMT2AMEN1TSHRALDH1A1HPGD | |
| SCHEMBL14998228 | 0.71 | HDAC3 (0.53) | KMT2AMEN1HDAC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |