Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779571 | 0.93 | ALDH1A1 (0.64) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL1006444 | 0.88 | HTT (0.71) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL9809224 | 0.85 | HPGD (0.66) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL11506841 | 0.84 | ALDH1A1 (0.63) | HPGDMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29199290 | 0.84 | HPGD (0.61) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL9716701 | 0.83 | ADRA2C (0.55) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL8725847 | 0.83 | ADRA2C (0.55) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL11506563 | 0.82 | ADRA2C (0.58) | HPGDMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11665290 | 0.81 | HDAC8 (0.64) | HPGDMEN1KMT2AALDH1A1GLA | |
| SCHEMBL18275347 | 0.80 | KMT2A (0.56) | HPGDMEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |