Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004019 | 0.79 | HDAC1 (0.71) | LMNAKMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL3648706 | 0.78 | NPC1 (0.55) | LMNAKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL11794866 | 0.77 | KMT2A (0.52) | LMNAKMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL1003665 | 0.77 | KMT2A (0.83) | KMT2AMEN1HDAC1HDAC6TSHR | |
| SCHEMBL27579062 | 0.77 | ALDH1A1 (0.55) | LMNAL3MBTL1HDAC1HDAC6TSHR | |
| SCHEMBL25138742 | 0.75 | HDAC1 (0.71) | LMNAKMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL28204817 | 0.75 | ALDH1A1 (0.49) | LMNAL3MBTL1HDAC1HDAC6TSHR | |
| SCHEMBL1003508 | 0.74 | HDAC1 (0.71) | LMNAKMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL9492055 | 0.74 | ALDH1A1 (0.63) | LMNAKMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL8586363 | 0.73 | MLYCD (0.48) | KMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025375-A1 | COMPOSITIONS AND METHODS OF TREATING AMYLOID DISEASE | TREVENTIS CORPORATION (US) | 2010-03-04 | — | — | WO | claimed |