Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | AQP1 | P29972 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.45 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | LDHB | P07195 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737275 | 0.91 | KDM4E (0.57) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL9738323 | 0.85 | KDM4E (0.56) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL574228 | 0.83 | ALDH1A1 (0.69) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL2741892 | 0.81 | KDM4E (0.67) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL10224099 | 0.81 | KDM4E (0.80) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11456584 | 0.80 | CA2 (0.74) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11456213 | 0.79 | CA2 (0.61) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11841124 | 0.79 | KDM4E (0.88) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11844037 | 0.78 | KDM4E (0.72) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11789130 | 0.78 | KDM4E (0.78) | KDM4EUSP2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991097-A | BORON HYDRIDE OR METAL BOROHYDRIDES AS REDUCING AGENT, LEWIS ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |