Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | AQP1 | P29972 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795232 | 0.85 | KDM4E (0.62) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL9737275 | 0.84 | KDM4E (0.57) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL9737111 | 0.84 | SCN1A (0.42) | CA2CYP2D6SCN1ASCN5ASCN8A | |
| SCHEMBL9736989 | 0.83 | CYP2D6 (0.40) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL9739881 | 0.80 | SCN1A (0.40) | KDM4EALDH1A1CA2CYP2D6SCN1A | |
| SCHEMBL9737268 | 0.77 | CA2 (0.66) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL574228 | 0.77 | ALDH1A1 (0.69) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL2741892 | 0.76 | KDM4E (0.67) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL10224099 | 0.75 | KDM4E (0.80) | KDM4EUSP2ALDH1A1LMNAHPGD | |
| SCHEMBL11456584 | 0.74 | CA2 (0.74) | KDM4EUSP2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145867-A | NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVES, AND THE USE THEREOF AS MEDICINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |