Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085863 | 0.79 | CYP2C9 (0.38) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL10400040 | 0.79 | POLB (0.43) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL2034964 | 0.79 | SMN1; SMN2 (0.37) | CYP2C19CA12CA1CA2CA9 | |
| SCHEMBL13790227 | 0.78 | GAA (0.42) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL1691829 | 0.78 | GAA (0.42) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL10457084 | 0.77 | CYP2C9 (0.43) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL689523 | 0.76 | CYP3A4 (0.41) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL5100575 | 0.76 | CYP3A4 (0.41) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL16761024 | 0.76 | CYP3A4 (0.41) | CYP2C9CYP2C19CYP3A4GAAPOLB | |
| SCHEMBL9304618 | 0.76 | CYP3A4 (0.41) | CYP2C9CYP2C19CYP3A4GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039796-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | ABC BIOSCIENCE AS (NO) | 2016-02-11 | — | — | US | disclosed |
| US-20160039796-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | ABC BIOSCIENCE AS (NO) | 2016-02-11 | — | — | US | disclosed |
| US-20160039796-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | ABC BIOSCIENCE AS (NO) | 2016-02-11 | — | — | US | disclosed |
| EP-2981251-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | ABC Bioscience AS (NO) | 2016-02-10 | — | — | EP | disclosed |
| CN-105120851-A | BARETTIN and derivatives thereof for medical use, in particular for the treatment of diseases related to oxidative stress or inflammation, and for preserving or washing organs | ABC BIOSCIENCE AS | 2015-12-02 | — | — | CN | disclosed |
| WO-2014162010-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | ABC BIOSCIENCE AS (NO) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014162010-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | ABC BIOSCIENCE AS (NO) | 2014-10-09 | — | — | WO | disclosed |
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039796-A1 | BARETTIN AND DERIVATIVES THEREOF FOR MEDICAL USE, IN PARTICULAR FOR THE TREATMENT OF DISEASES RELATED TO OXIDATIVE STRESS OR INFLAMMATION, AND FOR PRESERVING OR WASHING ORGANS | TYR, CAT, MPO | CYP2C9 2033/4885CYP2C19 930/4885CYP3A4 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.