SCHEMBL16761024

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL365852	0.86	CYP3A4 (0.39)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL17249688	0.81	ALDH1A1 (0.39)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL16979607	0.79	CYP3A4 (0.38)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL2992966	0.79	CYP3A4 (0.40)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL2646513	0.79	POLB (0.43)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL2984783	0.79	SMN1; SMN2 (0.37)	CYP2C19CA12CA1CA2CA9
	SCHEMBL18532983	0.78	GAA (0.41)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL16978355	0.78	CYP3A4 (0.34)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL9617315	0.78	LMNA (0.39)	CYP3A4CYP2C9CYP2C19GAAPOLB
	SCHEMBL14671697	0.78	CYP3A4 (0.42)	CYP3A4CYP2C9CYP2C19GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.