Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | SHBG | P04278 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.71 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.71 |
| ▸ | FNTA | P49354 | 4/20 | 0.58 |
| ▸ | FNTB | P49356 | 4/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845386 | 0.90 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| SCHEMBL11845368 | 0.90 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| SCHEMBL11852315 | 0.90 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| SCHEMBL10079789 | 0.89 | HSD17B10 (0.69) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL13026135 | 0.83 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL9926754 | 0.83 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL10089738 | 0.83 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL13332835 | 0.83 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL4888 | 0.83 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL6535496 | 0.83 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956349-A | TRIETHYL ORTHOACETATE, ACID CATALYST | SYNTEX (U.S.A.) INC. (US) | 1976-05-11 | — | — | US | disclosed |