Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | SHBG | P04278 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.69 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.69 |
| ▸ | FNTA | P49354 | 5/20 | 0.56 |
| ▸ | FNTB | P49356 | 5/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845368 | 0.89 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| SCHEMBL11845386 | 0.89 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| SCHEMBL11796127 | 0.89 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| SCHEMBL11852315 | 0.89 | HSD17B10 (0.71) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL11058433 | 0.82 | HSD17B10 (0.96) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL13332835 | 0.82 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL6535496 | 0.82 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL13026135 | 0.82 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL9926754 | 0.82 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR | |
| Cortisone SCHEMBL10089738 | 0.82 | HSD17B10 (1.00) | HSD17B10SERPINA6NR3C1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382288-B2 | Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2016-07-05 | — | — | US | disclosed |
| US-9382288-B2 | Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2016-07-05 | — | — | US | disclosed |
| US-20130266645-A1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-10-10 | — | — | US | disclosed |
| US-20130266645-A1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-10-10 | — | — | US | disclosed |
| WO-2012051988-A2 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130266645-A1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | HSD17B7, CYP21A2, CYP17A1 | HSD17B10 213/4885SERPINA6 46/4885NR3C1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.