Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ARF6 | P62330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180128 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL1180449 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL116957 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL13858869 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL9336031 | 0.75 | MAPK14 (0.39) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL27425532 | 0.71 | CUL4A (0.37) | KDM4EALDH1A1GLAGAAHPGD | |
| Thiocyanic Acid SCHEMBL29118523 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL8121255 | 0.70 | — | — | |
| SCHEMBL29118524 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL10591655 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746979-B1 | Use of pyrrole compounds as antifouling agents | BASF AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-5932520-A | FOR MARINE SURFACES | AMERICAN CYANAMID COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| EP-0746979-A1 | Use of pyrrole compounds as antifouling agents | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | claimed |
| EP-3231283-A1 | BIOCIDE COMPOSITION COMPRISING ZINC PYRITHIONE AND A PYRROLE DERIVATIVE | Arch Chemicals, Inc. (US) | 2017-10-18 | — | — | EP | disclosed |
| US-8481523-B2 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8372829-B2 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110143153-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110144232-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110104375-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-05-05 | — | — | US | disclosed |
| US-7893047-B2 | comprising zinc pyrithione, and 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile, present in a weight ratio of 3:2 to 2:3, and wherein biocidal composition is copper free or has low copper content | ARCH CHEMICALS, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20070207178-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2007-09-06 | — | — | US | disclosed |
| EP-0746979-B1 | Use of pyrrole compounds as antifouling agents | BASF AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-5932520-A | FOR MARINE SURFACES | AMERICAN CYANAMID COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0746979-A1 | Use of pyrrole compounds as antifouling agents | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207178-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | PYCR1, CAT, BBOX1 | KDM4E 3108/4885ALDH1A1 149/4885GLA 3145/4885 |
| US-20110144232-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | PYCR1, CAT, BBOX1 | KDM4E 3108/4885ALDH1A1 149/4885GLA 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.