Salicyladehyde

Salicyladehyde

SCHEMBL11796643

O=Cc1ccc([N+](=O)[O-])cc1.O=Cc1ccccc1O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.58
TRIM24 O15164 1/20 0.58
TRIM33 Q9UPN9 1/20 0.58
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
BAX Q07812 2/20 0.49
MAOB P27338 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
PTGS2 P35354 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
PTGS1 P23219 1/20 0.45
CCR6 P51684 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicyladehyde SCHEMBL27347838 0.93 TRIM24 (0.67) ERN1TRIM24TRIM33KMT2AMEN1
SCHEMBL12735606 0.82 PTGS2 (0.61) KMT2AMEN1CASP3SENP8SENP7
Dinitrophenylene SCHEMBL27533002 0.82 ERN1 (0.65) ERN1TRIM24TRIM33KMT2AMEN1
Benzaldehyde SCHEMBL4022100 0.81 ALDH1A1 (0.60) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL1157 0.80 APP (0.61) ERN1ALDH1A1MAPTPTGS2NPC1
4-Hydroxybenzaldehyde SCHEMBL4952623 0.79 TRIM24 (0.72) ERN1TRIM24TRIM33KMT2AMEN1
Salicyladehyde SCHEMBL4985603 0.79 TRIM24 (0.78) ERN1TRIM24TRIM33KMT2AMEN1
Benzaldehyde SCHEMBL27987141 0.79 ALDH1A1 (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL28981615 0.78 APP (0.59) ALDH1A1MAPTPTGS2NPC1RAB9A
Hydrochloric Acid SCHEMBL29016137 0.78 APP (0.59) ERN1ALDH1A1MAPTPTGS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3974137-A ANTIBACTERIAL, ALDEHYDE BLOCKING AGENT BRISTOL-MYERS COMPANY (US) 1976-08-10 US claimed