Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624782 | 0.92 | MAPT (0.46) | CTSLCTSBCTSKPOLBNPSR1 | |
| SCHEMBL10996019 | 0.87 | MAPT (0.50) | POLBNPSR1MAPTHTTCYP1A2 | |
| SCHEMBL10989410 | 0.77 | GRM5 (0.54) | CTSLCTSBCTSKMAPTHTT | |
| SCHEMBL967807 | 0.75 | MAPT (0.46) | CTSLCTSBCTSKPOLBNPSR1 | |
| SCHEMBL5993592 | 0.74 | THRB (0.42) | NPSR1MAPTHTTGAAALDH1A1 | |
| SCHEMBL28679508 | 0.74 | MAPT (0.52) | POLBNPSR1MAPTHTTCYP1A2 | |
| SCHEMBL10997322 | 0.73 | CA1 (0.47) | MAPTGAASMN1; SMN2IDO1ALDH1A1 | |
| SCHEMBL11309120 | 0.73 | ALDH1A1 (0.46) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL632551 | 0.72 | TDP1 (0.56) | POLBNPSR1MAPTHTTCYP1A2 | |
| SCHEMBL31174454 | 0.72 | TDP1 (0.56) | POLBNPSR1MAPTHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |