Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804456 | 0.87 | SMN1; SMN2 (0.47) | TP53EGFRERBB2KDM4AKDM4C | |
| SCHEMBL9125852 | 0.82 | TP53 (0.51) | TP53EGFRERBB2MTNR1AMTNR1B | |
| SCHEMBL14550169 | 0.80 | TP53 (0.49) | TP53NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11799862 | 0.80 | ALDH1A1 (0.47) | TP53EGFRERBB2MTNR1AMTNR1B | |
| SCHEMBL8018555 | 0.80 | KMT2A (0.54) | TP53MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL11591464 | 0.79 | SMN1; SMN2 (0.46) | TP53EGFRERBB2RAB9AKMT2A | |
| SCHEMBL11851063 | 0.79 | ATG4B (0.55) | TP53EGFRERBB2NPC1RAB9A | |
| SCHEMBL11797772 | 0.79 | SMN1; SMN2 (0.41) | TP53EGFRERBB2KDM4AKDM4C | |
| Hydrochloric Acid SCHEMBL8940098 | 0.79 | KMT2A (0.53) | TP53NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL547806 | 0.78 | TDP1 (0.43) | TP53MTNR1AMTNR1BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |