Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706798 | 0.91 | TSHR (0.43) | TSHRCYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL11705870 | 0.84 | DHFR (0.40) | TSHRCYP3A4MAPK1ALDH1A1POLB | |
| SCHEMBL16372585 | 0.84 | RARB (0.41) | TSHRCYP3A4MAPK1ALDH1A1RARB | |
| SCHEMBL3342982 | 0.83 | TSHR (0.43) | TSHRCYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL17735425 | 0.81 | MAPT (0.50) | TSHRCYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL3341078 | 0.81 | MAOA (0.43) | TSHRCYP3A4MAPK1ALDH1A1POLB | |
| SCHEMBL27224315 | 0.80 | ESR1 (0.44) | TSHRCYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL455549 | 0.79 | ALDH1A1 (0.41) | TSHRCYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL29353325 | 0.79 | ALDH1A1 (0.41) | TSHRCYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL12000686 | 0.79 | LOX (0.40) | TSHRCYP3A4MAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956267-A | Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |