Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | DRD1 | P21728 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790502 | 0.88 | HTR1A (0.69) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| SCHEMBL16986158 | 0.87 | TSHR (0.70) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| Hydrochloric Acid SCHEMBL16986155 | 0.86 | TSHR (0.72) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| SCHEMBL20254428 | 0.81 | MEN1 (0.78) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| Melperone SCHEMBL146287 | 0.80 | KMT2A (1.00) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| SCHEMBL11415059 | 0.80 | MEN1 (0.76) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| Hydrochloric Acid SCHEMBL30658979 | 0.80 | MEN1 (0.76) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| SCHEMBL12123771 | 0.79 | ALDH1A1 (0.73) | HTR1AKMT2ALMNA | |
| Melperone SCHEMBL1649537 | 0.79 | KMT2A (0.97) | HTR1ADRD3CHRM2ADRA2ADRD1 | |
| Lenperone SCHEMBL121686 | 0.79 | MEN1 (0.74) | HTR1ADRD3CHRM2ADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936468-A | PSYCHOTROPIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-03 | — | — | US | disclosed |