Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.69 |
| ▸ | DRD1 | P21728 | 3/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.69 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797372 | 0.88 | HTR1A (0.66) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| Primaperone SCHEMBL310299 | 0.87 | TSHR (0.74) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| Primaperone SCHEMBL364809 | 0.85 | TSHR (0.76) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| SCHEMBL4496558 | 0.85 | TSHR (0.76) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| SCHEMBL5201062 | 0.84 | ALDH1A1 (0.59) | ADRA1ADRD3KMT2ADRD2KDM4E | |
| Azabuperone SCHEMBL2111662 | 0.83 | DRD3 (0.60) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| SCHEMBL20254428 | 0.83 | MEN1 (0.78) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| Melperone SCHEMBL146287 | 0.82 | KMT2A (1.00) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| SCHEMBL11415059 | 0.82 | MEN1 (0.76) | HTR1AADRA2ADRD1ADRA1ADRD3 | |
| Hydrochloric Acid SCHEMBL30658979 | 0.82 | MEN1 (0.76) | HTR1AADRA2ADRD1ADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936468-A | PSYCHOTROPIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-03 | — | — | US | disclosed |