Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704376 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11591034 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9667499 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1532370 | 0.83 | MAPT (0.66) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9667707 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10889343 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5523947 | 0.81 | KCNMA1 (0.64) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7088418 | 0.80 | KMT2A (0.63) | ALDH1A1KCNMA1RAB9AMAPTNPSR1 | |
| SCHEMBL10977960 | 0.79 | RAB9A (0.63) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9364781 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KCNMA1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993674-A | ANTIULCER, BRONCHODILATOR, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3988294-A | Surface coating compositions containing antimicrobic ureas | R. T. VANDERBILT COMPANY, INC. (US) | 1976-10-26 | — | — | US | disclosed |