SCHEMBL11798809

SCHEMBL11798809

CC(Cl)C(CC(=O)O)(C(=O)O)C(C)Cl

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.39
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
ACLY P53396 3/20 0.35
CPT2 P23786 2/20 0.35
KDM4E B2RXH2 1/20 0.33
FFAR1 O14842 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSPD1 P10809 1/20 0.31
BLM P54132 1/20 0.31
HSPE1 P61604 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1643768 0.80 CYP2C19 (0.46) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL1049551 0.78 CYP2C19 (0.44) CYP2C19HIF1ACYP2D6TSHRALDH1A1
Succinic Acid SCHEMBL7712865 0.74 LMNA (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL10954161 0.73 HMGCR (0.46) CYP2C19HIF1ACYP2D6TSHRALDH1A1
Citric Acid SCHEMBL28125108 0.71 ALDH1A1 (0.71) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL10010577 0.71 CYP2D6 (0.38) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL1301902 0.70 CYP2D6 (0.37) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL11655018 0.69 HSPD1 (0.44) CYP2C19HIF1ACYP2D6TSHRFFAR1
SCHEMBL1706942 0.67
SCHEMBL11804553 0.67 CPT2 (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3976627-A Vulcanizable compositions of carboxyl-containing polymers THE B.F. GOODRICH COMPANY (US) 1976-08-24 US disclosed