Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801077 | 0.87 | HSD11B1 (0.38) | ALDH1A1CYP3A4ALOX5HSD11B1MEN1 | |
| SCHEMBL11798835 | 0.80 | ALOX5 (0.40) | ALDH1A1CYP3A4ALOX5HSD11B1MEN1 | |
| SCHEMBL11796312 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HSD11B1DDB1CRBN | |
| SCHEMBL11796449 | 0.76 | ALOX5 (0.42) | ALOX5HSD11B1MEN1KMT2A | |
| SCHEMBL11803104 | 0.74 | ALOX5 (0.53) | ALOX5HSD11B1MEN1KMT2ANPSR1 | |
| SCHEMBL11797567 | 0.72 | ALOX5 (0.45) | ALDH1A1ALOX5HSD11B1MEN1KMT2A | |
| SCHEMBL11799978 | 0.71 | ALOX5 (0.40) | ALDH1A1ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL11797538 | 0.71 | ALOX5 (0.42) | ALDH1A1ALOX5DDB1CRBNPARP1 | |
| SCHEMBL17543803 | 0.71 | PSEN1 (0.41) | ALDH1A1ALOX5HSD11B1SRD5A1 | |
| SCHEMBL11793984 | 0.69 | ALOX5 (0.40) | ALDH1A1CYP3A4ALOX5HSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965180-A | CNS DEPRESSANT | THE UPJOHN COMPANY (US) | 1976-06-22 | — | — | US | disclosed |