Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800920 | 0.91 | PDK1 (0.51) | PDK1TPMTMEN1KMT2APDK3 | |
| SCHEMBL11796921 | 0.80 | PDK1 (0.58) | PDK1VCAM1 | |
| SCHEMBL29240575 | 0.80 | TPMT (0.61) | TPMTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5220434 | 0.80 | TPMT (0.81) | TPMTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5216905 | 0.78 | TPMT (0.64) | TPMTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7430461 | 0.76 | TPMT (0.54) | TPMTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8728234 | 0.76 | TPMT (0.54) | TPMTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29493658 | 0.74 | TPMT (0.55) | TPMTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1447496 | 0.74 | TPMT (0.55) | TPMTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11799063 | 0.74 | GPR35 (0.56) | PDK1PDK3PDK4ALDH1A1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |