Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.51 |
| ▸ | TPMT | P51580 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11799798 | 0.91 | PDK1 (0.56) | PDK1TPMTALDH1A1LMNAMAPT | |
| SCHEMBL1190543 | 0.84 | TPMT (0.70) | TPMTALDH1A1LMNAMAPTRAF1 | |
| SCHEMBL1191207 | 0.84 | TPMT (0.54) | TPMTALDH1A1LMNAMAPTRAF1 | |
| SCHEMBL11805116 | 0.83 | ALDH1A1 (0.56) | PDK1TPMTALDH1A1LMNAHPGD | |
| SCHEMBL4892239 | 0.82 | TPMT (0.56) | TPMTALDH1A1LMNAMAPTRAF1 | |
| SCHEMBL12727245 | 0.79 | TPMT (0.49) | TPMTALDH1A1LMNAMAPTRAF1 | |
| SCHEMBL11799063 | 0.79 | GPR35 (0.56) | PDK1ALDH1A1VCAM1PDK3PDK4 | |
| SCHEMBL11796921 | 0.75 | PDK1 (0.58) | PDK1VCAM1 | |
| SCHEMBL6701537 | 0.75 | TSHR (0.48) | TPMTALDH1A1LMNAMAPTRAF1 | |
| SCHEMBL28043007 | 0.73 | MAPK1 (0.49) | TPMTALDH1A1LMNAMAPTRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |