SCHEMBL11799947

SCHEMBL11799947

O=C(/C=C\C(=O)OC(=O)c1ccccc1C(=O)O)OC(=O)c1ccccc1C(=O)O.[SnH4].[SnH4]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.55
HPGD P15428 3/20 0.55
HSD17B10 Q99714 3/20 0.55
MAPT P10636 2/20 0.55
ALDH1A1 P00352 9/20 0.54
ALOX15 P16050 1/20 0.54
AKR1C3 P42330 1/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HMGB1 P09429 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA9 Q16790 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
CA14 Q9ULX7 1/20 0.42
HDAC8 Q9BY41 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297322 0.98 KDM4E (0.56) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL14920339 0.96 KDM4E (0.55) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL25290328 0.87 ALDH1A1 (0.48) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL33469 0.86 HCAR2 (0.50) KDM4EHPGDHSD17B10MAPTALDH1A1
Ethane SCHEMBL15524474 0.86 ALDH1A1 (0.47) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL29393238 0.83 ALDH1A1 (0.70) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL713624 0.83 ALDH1A1 (0.70) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL248317 0.83 ALDH1A1 (0.70) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL335929 0.83 ALDH1A1 (0.52) KDM4EHPGDHSD17B10MAPTALDH1A1
SCHEMBL29693542 0.83 ALDH1A1 (0.52) KDM4EHPGDHSD17B10MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3953639-A Mechanically embossed resilient laminar floor material ARMSTRONG CORK COMPANY (US) 1976-04-27 US disclosed