SCHEMBL297322

SCHEMBL297322

O=C(/C=C\C(=O)OC(=O)c1ccccc1C(=O)O)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
HSD17B10 Q99714 5/20 0.56
HPGD P15428 4/20 0.56
MAPT P10636 2/20 0.56
ALDH1A1 P00352 8/20 0.56
ALOX15 P16050 1/20 0.56
AKR1C3 P42330 1/20 0.45
HMGB1 P09429 2/20 0.43
NAPRT Q6XQN6 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
HDAC8 Q9BY41 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11799947 0.98 KDM4E (0.55) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL14920339 0.98 KDM4E (0.55) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL25290328 0.89 ALDH1A1 (0.48) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL33469 0.88 HCAR2 (0.50) KDM4EHSD17B10HPGDMAPTALDH1A1
Ethane SCHEMBL15524474 0.88 ALDH1A1 (0.47) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL29393238 0.85 ALDH1A1 (0.70) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL713624 0.85 ALDH1A1 (0.70) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL248317 0.85 ALDH1A1 (0.70) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL335929 0.85 ALDH1A1 (0.52) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL29693542 0.85 ALDH1A1 (0.52) KDM4EHSD17B10HPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066365-B1 ACIDIC COMPOSITION CONTAINING FLUORIDE FOR REMOVAL OF PHOTORESISTS AND ETCH RESIDUES AIR PROD & CHEM (US) 2009-08-05 EP claimed
US-6037385-A LIQUID ACRYLIC-URETHANE PREPOLYMER AS DILUENT ADDITIVE; REDUCED STYRENE; STORAGE STABILITY, HANDLING, SHELF LIFE HEHR INTERNATIONAL INC. (US) 2000-03-14 US claimed
CN-101883795-B Cross-linkable vinylester-copolymers and use thereof as low-profile-additives WACKER CHEMIE AG 2012-12-12 CN disclosed
EP-1557724-B1 Photoconductive imaging members XEROX CORP (US) 2012-03-14 EP disclosed
CN-101883823-A Free radical crosslinkable polymer composition containing epoxy-functional copolymer WACKER CHEMIE AG 2010-11-10 CN disclosed
CN-101883795-A Cross-linkable vinylester-copolymers and use thereof as low-profile-additives WACKER CHEMIE AG 2010-11-10 CN disclosed
US-6773564-B1 REACTION LAYER CONTAINS PHTHALIC ACID OR A PHTHALATE, AND A GLUCOSE DEHYDROGENASE WHOSE COENZYME IS PYRROLO-QUINOLINE QUINONE; STABILIZER; BIOSENSOR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-08-10 US disclosed
US-6667017-B2 Structured packing and monoliths each having a catalyst for oxidizing volatile organic compounds; corrugated mesh-like sheets are arrangeed in mirror image angular relative orientations relative to input gas flow direction ABB LUMMUS GLOBAL, INC. 2003-12-23 US disclosed
US-20020141912-A1 Environmentally harmful compound oxidation catalyst supported on a mesh-like structure ABB LUMMUS GLOBAL, INC. 2002-10-03 US disclosed
US-6248862-B1 PRODUCED BY CULTIVATING A PHA-PRODUCING MICROORGANISM IN THE PRESENCE OF AN ALIPHATIC DIOL OR AN ALIPHATIC POLYOL. MONSANTO COMPANY 2001-06-19 US disclosed
US-4369224-A Glass fiber reinforced laminate FREEMAN CHEMICAL CORPORATION (US) 1983-01-18 US disclosed
US-4295907-A Method of making glass fiber reinforced laminate FREEMAN CHEMICAL CORPORATION (US) 1981-10-20 US disclosed
US-4285871-A Process for continuously separating phthalic anhydride from the reaction gases of the catalytic oxidation of o-xylene and/or naphthalene DAVY INTERNATIONAL AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed
US-4207224-A Plastics composition CIBA-GEIGY AG (CH) 1980-06-10 US disclosed