SCHEMBL33469

SCHEMBL33469

O=C(O)/C=C\C(=O)OC(=O)c1ccccc1C(=O)OC(=O)/C=C\C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.50
HPGD P15428 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 5/20 0.42
HDAC3 O15379 1/20 0.42
TNKS O95271 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7299840 0.89 HPGD (0.51) HCAR2HPGDKDM4EMAPTHSD17B10
SCHEMBL297322 0.88 KDM4E (0.56) HPGDKDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL23357451 0.88 ALDH1A1 (0.51) HCAR2HPGDKDM4EMAPTHSD17B10
SCHEMBL14920339 0.86 KDM4E (0.55) HPGDKDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL11799947 0.86 KDM4E (0.55) HPGDKDM4EMAPTHSD17B10SMN1; SMN2
SCHEMBL240024 0.86 HSD17B10 (0.65) HCAR2HPGDKDM4EMAPTHSD17B10
SCHEMBL28259523 0.86 ALDH1A1 (0.50) HCAR2HPGDKDM4EMAPTHSD17B10
SCHEMBL21678774 0.85 SMN1; SMN2 (0.50) HPGDKDM4EMAPTHSD17B10HTT
Maleic Acid SCHEMBL3674038 0.84 ALDH1A1 (0.56) HCAR2HPGDKDM4EMAPTHSD17B10
SCHEMBL3235668 0.84 HCAR2 (0.50) HCAR2MAPTHSD17B10SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4359368-A1 COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE WockLab GmbH & Co. KG (DE) 2024-05-01 EP claimed
WO-2022268777-A1 COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE WOCKLAB GMBH & CO. KG (DE) 2022-12-29 WO claimed
US-11539074-B2 Artificial solid electrolyte interface (A-SEI) cap layer including graphene layers with flexible wrinkle areas Lyten, Inc. (US) 2022-12-27 US claimed
US-20210126287-A1 ARTIFICIAL SOLID ELECTROLYTE INTERFACE (A-SEI) CAP LAYER INCLUDING GRAPHENE LAYERS WITH FLEXIBLE WRINKLE AREAS Lyten, Inc. (US) 2021-04-29 US claimed
US-20210126286-A1 ARTIFICIAL SOLID ELECTROLYTE INTERFACE CAP LAYER FOR AN ANODE IN A LI S BATTERY SYSTEM Lyten, Inc. (US) 2021-04-29 US claimed
CN-114471697-B Treatment method of titanium-containing molecular sieve 中国石油化工股份有限公司 2024-06-11 CN disclosed
US-11735740-B2 Protective carbon layer for lithium (Li) metal anodes Lyten, Inc. (US) 2023-08-22 US disclosed
US-11631893-B2 Artificial solid electrolyte interface cap layer for an anode in a Li S battery system Lyten, Inc. (US) 2023-04-18 US disclosed
US-20230067032-A1 PROTECTIVE CARBON LAYER FOR LITHIUM (LI) METAL ANODES Lyten, Inc. (US) 2023-03-02 US disclosed
US-11539074-B2 Artificial solid electrolyte interface (A-SEI) cap layer including graphene layers with flexible wrinkle areas Lyten, Inc. (US) 2022-12-27 US disclosed
WO-2022056008-A1 ARTIFICIAL SOLID ELECTROLYTE INTERFACE CAP LAYER FOR AN ANODE IN A LI S BATTERY SYSTEM Lyten, Inc. (US) 2022-03-17 WO disclosed
US-20210126286-A1 ARTIFICIAL SOLID ELECTROLYTE INTERFACE CAP LAYER FOR AN ANODE IN A LI S BATTERY SYSTEM Lyten, Inc. (US) 2021-04-29 US disclosed
US-20130053508-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-28 US disclosed
US-8349962-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-08 US disclosed
EP-2470616-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M Innovative Properties Company (US) 2012-07-04 EP disclosed
US-20120028043-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2012-02-02 US disclosed
US-8067504-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-29 US disclosed
WO-2011025651-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-03 WO disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed
US-4285871-A Process for continuously separating phthalic anhydride from the reaction gases of the catalytic oxidation of o-xylene and/or naphthalene DAVY INTERNATIONAL AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS AAAS, PTK2, MDN1 HCAR2 1226/4885HPGD 161/4885KDM4E 859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.