Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | PLAT | P00750 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400079 | 0.86 | ELANE (0.56) | F2PLAUPLATELANEKLK1 | |
| SCHEMBL10458677 | 0.83 | AKR1C3 (0.50) | RAB9ANPC1AKR1C3HTR2AIDO1 | |
| SCHEMBL11795459 | 0.82 | ELANE (0.47) | RAB9ANPC1F2PLAUPLAT | |
| SCHEMBL11801782 | 0.80 | KMT2A (0.46) | RAB9ANPC1AKR1C3ELANEHTR2A | |
| SCHEMBL11795463 | 0.80 | RAB9A (0.43) | RAB9ANPC1F2PLAUPLAT | |
| SCHEMBL6559779 | 0.77 | RAB9A (0.56) | RAB9ANPC1AKR1C3HTR2AIDO1 | |
| SCHEMBL17126253 | 0.77 | KLK1 (0.76) | F2PLAUPLATELANEKLK1 | |
| SCHEMBL7737719 | 0.76 | RAB9A (0.55) | RAB9ANPC1IDO1 | |
| SCHEMBL18953048 | 0.76 | BTN3A1 (0.52) | RAB9ANPC1ELANEHTR2A | |
| SCHEMBL18973479 | 0.76 | BTN3A1 (0.52) | RAB9ANPC1ELANEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |