Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801441 | 0.80 | ALDH1A1 (0.41) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL11799965 | 0.80 | RAB9A (0.50) | MAPTRAB9ANPC1AKR1C3ELANE | |
| SCHEMBL11795463 | 0.77 | RAB9A (0.43) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL11795459 | 0.77 | ELANE (0.47) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL11802813 | 0.76 | MIF (0.46) | KMT2AMEN1KDM4EALDH1A1RAB9A | |
| SCHEMBL10459830 | 0.74 | MIF (0.44) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL11388720 | 0.74 | MIF (0.43) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL16485402 | 0.73 | RAB9A (0.45) | MAPTALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL17126253 | 0.72 | KLK1 (0.76) | ELANE | |
| SCHEMBL18953048 | 0.71 | BTN3A1 (0.52) | KMT2AMEN1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |