Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
| ▸ | KLK1 | P06870 | 4/20 | 0.54 |
| ▸ | PLAU | P00749 | 7/20 | 0.54 |
| ▸ | F2 | P00734 | 6/20 | 0.54 |
| ▸ | PLAT | P00750 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 6/20 | 0.51 |
| ▸ | KLK8 | O60259 | 5/20 | 0.51 |
| ▸ | KLK4 | Q9Y5K2 | 5/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | KLK2 | P20151 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 1/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11799965 | 0.86 | RAB9A (0.50) | ELANEKLK1PLAUF2PLAT | |
| SCHEMBL31244589 | 0.83 | ALDH1A1 (0.50) | ELANELAP3 | |
| SCHEMBL7282986 | 0.81 | POLB (0.49) | ELANELAP3 | |
| SCHEMBL10458230 | 0.80 | ELANE (0.47) | ELANEPLAUF2PLATPLG | |
| SCHEMBL10458711 | 0.79 | ANPEP (0.41) | ELANEKLK1PLAUF2PLAT | |
| SCHEMBL28290493 | 0.78 | ALDH1A1 (0.59) | LAP3 | |
| SCHEMBL10459006 | 0.76 | MEN1 (0.44) | ELANEKLK1PLAUANPEPLAP3 | |
| SCHEMBL2678810 | 0.75 | ELANE (0.44) | ELANEKLK1PLAUF2PLAT | |
| SCHEMBL7694383 | 0.75 | ALDH1A1 (0.59) | LAP3 | |
| SCHEMBL5689257 | 0.74 | ELANE (0.77) | ELANEKLK1PLAUF2PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937331-A | Chemical intermediates for antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0334593-A1 | Chiral azetidinone epoxides | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-09-27 | — | — | EP | disclosed |