Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13551804 | 0.89 | PYCR1 (0.47) | ALDH1A1PYCR1CYP2C19LTA4H | |
| SCHEMBL11791442 | 0.86 | PYCR1 (0.47) | NR3C1SLC6A4ALDH1A1MAPTPYCR1 | |
| SCHEMBL15471256 | 0.79 | PYCR1 (0.51) | ALDH1A1MAPTPYCR1LTA4HMEN1 | |
| SCHEMBL11795730 | 0.77 | SLC6A4 (0.48) | NR3C1HTR2ASLC6A4ALDH1A1POLB | |
| SCHEMBL17147385 | 0.73 | TEAD4 (0.54) | MMP13TEAD4ALDH1A1POLBMAPT | |
| SCHEMBL17886950 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TDP1LTA4HMEN1KMT2A | |
| SCHEMBL8250784 | 0.72 | LTA4H (0.43) | ALDH1A1POLBTDP1LTA4H | |
| SCHEMBL10013919 | 0.72 | TEAD4 (0.56) | MMP13TEAD4ALDH1A1POLBMAPT | |
| SCHEMBL9234713 | 0.72 | TEAD4 (0.56) | MMP13TEAD4ALDH1A1POLBMAPT | |
| SCHEMBL19360417 | 0.72 | TEAD4 (0.56) | MMP13TEAD4ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3946119-A | Optionally substituted α-tertiary butyl-p-phenoxybenzylamines and their use as hypolipidemic agents | SANDOZ, INC. (US) | 1976-03-23 | — | — | US | disclosed |