Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879281 | 0.84 | MAPT (0.48) | MAPTGAALMNACA12CA1 | |
| SCHEMBL11800566 | 0.84 | CA2 (0.45) | MAPTGAACA12CA1CA2 | |
| SCHEMBL11783509 | 0.82 | MAPT (0.60) | MAPTGAALMNACA12CA1 | |
| SCHEMBL11800292 | 0.79 | LMNA (0.60) | MAPTGAALMNACA12CA1 | |
| Acetanilide SCHEMBL11800242 | 0.79 | L3MBTL1 (0.48) | MAPTGAALMNACA12CA1 | |
| SCHEMBL11803709 | 0.78 | CA2 (0.39) | GAALMNACA12CA1CA2 | |
| SCHEMBL2883320 | 0.78 | MAPT (0.49) | MAPTGAALMNACA12CA1 | |
| SCHEMBL11802086 | 0.77 | CISD1 (0.45) | MAPTGAALMNACA12CA1 | |
| SCHEMBL11804843 | 0.77 | CA2 (0.38) | MAPTGAALMNACA12CA1 | |
| SCHEMBL11799351 | 0.76 | CA2 (0.53) | LMNACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992440-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3982018-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |