Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 4/20 | 0.30 |
| ▸ | CES1 | P23141 | 4/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812204 | 0.78 | THRB (0.32) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL11812208 | 0.78 | THRB (0.32) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL11294459 | 0.74 | CES2 (0.45) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL28407024 | 0.69 | TSHR (0.44) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL27255307 | 0.69 | TSHR (0.44) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL28832704 | 0.69 | TSHR (0.44) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL6562270 | 0.68 | EPHX1 (0.44) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL11804564 | 0.68 | CES2 (0.36) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL11804559 | 0.68 | CES2 (0.36) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL6859403 | 0.67 | ALDH1A1 (0.38) | CES2THRBHSD17B10GMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3963683-A | Rubber formulations containing vulcanization inhibiting thioformamidine compounds | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-06-15 | — | — | US | disclosed |