Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752463 | 0.78 | MAPT (0.41) | KDM4EHSD17B10KMT2AMEN1MAPK1 | |
| SCHEMBL610664 | 0.78 | MAPT (0.41) | KDM4EHSD17B10KMT2AMEN1MAPK1 | |
| SCHEMBL11727816 | 0.76 | DPP4 (0.46) | KDM4EHSD17B10MAPK1CSNK2A1ALDH1A1 | |
| SCHEMBL10471341 | 0.76 | TTR (0.52) | KDM4EHSD17B10KMT2AMEN1MAPK1 | |
| SCHEMBL11577299 | 0.74 | LMNA (0.39) | HSD17B10KMT2ALMNACDC7PLK4 | |
| SCHEMBL9031190 | 0.72 | ALDH1A1 (0.49) | KDM4EHSD17B10KMT2AMEN1MAPK1 | |
| SCHEMBL10371881 | 0.72 | ALDH1A1 (0.43) | KDM4EHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL11504756 | 0.72 | CYP3A4 (0.48) | KDM4EHSD17B10MAPK1CSNK2A1ALDH1A1 | |
| SCHEMBL31043497 | 0.72 | LMNA (0.40) | KDM4EHSD17B10KMT2AMEN1MAPK1 | |
| SCHEMBL8530875 | 0.71 | KDM4E (0.56) | KDM4EHSD17B10KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933869-A | Preparation of organic radiohalogen compounds | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | claimed |
| US-3933869-A | Preparation of organic radiohalogen compounds | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |