Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757716 | 0.81 | ALDH1A1 (0.62) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL866784 | 0.79 | GSK3B (0.61) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL11065047 | 0.78 | RAB9A (0.58) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL20055247 | 0.78 | HPGD (0.58) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL15706788 | 0.77 | RAB9A (0.76) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL16398364 | 0.77 | RAB9A (1.00) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL15396003 | 0.77 | RAB9A (0.57) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL11430934 | 0.76 | GSK3B (0.57) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL11430938 | 0.76 | GSK3B (0.57) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL4575816 | 0.75 | NPC1 (0.58) | RAB9ANPC1HPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |